“ Mining in a certain area turns all exposed skin (maybe just parts that are actively disturbing the chemicals that cause the reaction) of the those doing the mining to a dark blue color. Will wear off taking as many years/days spent in the mine. ... meeting a party of blue-skinned humans armed with pick-axes etc. Strange disease? Demon offspring? Curse? If they meet only one ex-worker, they will very carefully listen to any stories he says, no matter if drunken or insane, or just makes up to get a beer.”
“ Trapped in his tomb, but alive, the God of Pain awaits his uleashing, said to be at the end of the world, he uses his only powers he can and calls to him 2 people, a man and a women to reliquish him from his prison. The man and the women, decieved by them thinking it a person trapped, go after to help the God of Pain unwittily and let him destroy the world”
“ The PC's enter a town amid a giant celebration, the Spring Wedding Festival. Unmarried men and women from all over the provinces gather her every spring to be matched by the most sacred matchmaker ever to live, Holly Lovard. Holly is now ancient and must be carried everywhere she visits and rumors are that this will be her last visit to the Wedding Festival so any matches made this spring will be doubley blessed.
Enter PC's, wrong place at the wrong time. Molly sees one of them, calls him/her out of the crowd and that are unable to resist the push and pull of the mob. Brought in front of Molly Lovard, the PC is declared the lifemate of <insert anybody>.
Could be the king's daughter, a peasant, member of the thieves guild. Could be anything to add a twist to an already building plot, or just throw the characters into an awkward situation.”